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Best med spas in Sioux Falls

20 clinics · ranked by rating & reviews · updated 2026

Sioux Falls is South Dakota's largest med spa market, spanning downtown, western Sioux Falls and the Cathedral District across the wider metro. Demand is steady for injectables (Botox, Dysport and fillers), laser hair removal, medical weight loss, microneedling and facials. Providers range from dermatology and plastic-surgery practices to boutique aesthetic studios, so credentials and pricing vary. Look for a licensed medical director, an experienced injector and transparent per-unit pricing rather than ratings alone. The clinics below are ranked by Google review volume and rating, so you can start with the most established Sioux Falls options and filter by the treatment you need.

Typical pricing

Typical Sioux Falls pricing: roughly $11–15 per unit for Botox, $575–1,000 per syringe for filler, and $160–340 per session for HydraFacial or microneedling. Packages and memberships are common — confirm the rate at consultation.

Browse by treatment

Laser Hair Removal (3) Botox & Dysport (10) Lip & Dermal Fillers (9) CoolSculpting (4) HydraFacial (1) Microneedling (5) Weight Loss (GLP-1) (6)

Top-rated med spas in Sioux Falls

  1. 1
    Refined Aesthetics
    Med Spa

    Refined Aesthetics

    Sioux falls

    Medical spa in Sioux Falls, SD · 5★ (721).

    ★ 5 · 721View →
  2. 2
    Serenity Spa & Facials Sioux Falls
    Med Spa

    Serenity Spa & Facials Sioux Falls

    Sioux falls

    Facial spa in Sioux Falls, SD · 4.8★ (529).

    ★ 4.8 · 529View →
  3. 3
    JMed Spa
    Med Spa

    JMISKO surgical design | md

    Sioux falls

    Medical spa in Sioux Falls, SD · 4.9★ (466).

    ★ 4.9 · 466View →
  4. 4
    Encompass Wellness & Aesthetics
    Med Spa

    Encompass Wellness & Aesthetics

    Sioux falls

    Wellness center in Sioux Falls, SD · 4.9★ (415).

    ★ 4.9 · 415View →
  5. 5
    Vital Flow Infusions
    Med Spa

    Vital Flow Infusions

    Sioux falls

    Medical spa in Downtown, SD · 5★ (268).

    ★ 5 · 268View →
  6. 6
    Novo Aesthetics
    Med Spa

    Novo Aesthetics

    Sioux falls

    Medical spa in Sioux Falls, SD · 5★ (228).

    ★ 5 · 228View →
  7. 7
    Infinity Medical Aesthetics
    Med Spa

    Infinity Medical Aesthetics

    Sioux falls

    Medical spa in Sioux Falls, SD · 5★ (197).

    ★ 5 · 197View →
  8. 8
    Liv Med Spa | Sioux Falls, SD
    Med Spa

    Liv Med Spa | Sioux Falls, SD

    Sioux falls

    Medical spa in Sioux Falls, SD · 5★ (153).

    ★ 5 · 153View →
  9. 9
    LMed Spa
    Med Spa

    Lazaderm

    Sioux falls

    Medical spa in Sioux Falls, SD · 4.9★ (140).

    ★ 4.9 · 140View →
  10. 10
    Artisan Skin and Laser Center
    Med Spa

    Artisan Skin and Laser Center

    Sioux falls

    Medical spa in Sioux Falls, SD · 4.9★ (136).

    ★ 4.9 · 136View →
  11. 11
    The Confidence Collective
    Med Spa

    The Confidence Collective

    Sioux falls

    Medical spa in Sioux Falls, SD · 5★ (133).

    ★ 5 · 133View →
  12. 12
    CMed Spa
    Med Spa

    Chapter Aesthetic Studio

    Sioux falls

    Medical spa in Sioux Falls, SD · 4.8★ (83).

    ★ 4.8 · 83View →
  13. 13
    KJ Relaxin Medical Spa
    Med Spa

    KJ Relaxin Medical Spa

    Sioux falls

    Medical spa in Sioux Falls, SD · 4.9★ (82).

    ★ 4.9 · 82View →
  14. 14
    Vibe Med Spa
    Med Spa

    Vibe Med Spa

    Sioux falls

    Medical spa in Sioux Falls, SD · 5★ (77).

    ★ 5 · 77View →
  15. 15
    Kalon Aesthetics & Surgery
    Med Spa

    Kalon Aesthetics & Surgery

    Sioux falls

    Medical spa in Sioux Falls, SD · 5★ (60).

    ★ 5 · 60View →
  16. 16
    Lisa's Lil Spa Room
    Med Spa

    Lisa's Lil Spa Room

    Sioux falls

    Facial spa in Sioux Falls, SD · 4.7★ (57).

    ★ 4.7 · 57View →
  17. 17
    DMed Spa
    Med Spa

    D'LUX SUITES ON TECHNOPOLIS DR

    Sioux falls

    Beauty salon in Sioux Falls, SD · 5★ (53).

    ★ 5 · 53View →
  18. 18
    Etched Medical Spa
    Med Spa

    Etched Medical Spa

    Sioux falls

    Medical spa in Sioux Falls, SD · 4.9★ (52).

    ★ 4.9 · 52View →
  19. 19
    LMed Spa
    Med Spa

    Legacy Med Spa

    Sioux falls

    Medical spa in Tea, SD · 5★ (46).

    ★ 5 · 46View →
  20. 20
    Skin Sanctuary
    Med Spa

    Skin Sanctuary

    Sioux falls

    Medical spa in Tea, SD · 5★ (42).

    ★ 5 · 42View →

FAQ

Med spas in Sioux Falls — common questions

How much does Botox cost in Sioux Falls? +
Most Sioux Falls med spas charge about $11–15 per unit, and a typical treatment uses 20–40 units. Confirm the per-unit rate and number of units quoted before booking.
Are med spas in South Dakota regulated? +
Medical spas in South Dakota operate under a licensed physician, and injectables and laser treatments should be performed or supervised by qualified medical professionals. Look for a named medical director and licensed injectors.
What should I look for when choosing a med spa in Sioux Falls? +
Prioritize a licensed medical team, transparent pricing, real before-and-after photos and a consultation before any treatment. High review counts help, but verify credentials first.
Which Sioux Falls areas have the most med spas? +
Downtown, western Sioux Falls and the Cathedral District have the highest concentration. Use the list below to compare clinics by rating, reviews and treatments.