Med spas in South Dakota
Compare 20 top-rated med spas and aesthetic clinics across South Dakota — by treatment, price and reviews. Pick a city to start.
20
Clinics listed
1
City
4.94
Avg Google rating
$11–$15
Botox / unit
Cities in South Dakota
Med spa costs in South Dakota
Across South Dakota, Botox typically runs about $11–$15 per unit. Since a common treatment uses 20–40 units, a single session usually costs roughly $220–$600, while dermal fillers generally run several hundred dollars per syringe. Prices vary by city, provider and product — open a city below for local per-unit ranges and typical filler, HydraFacial and microneedling pricing.
Top-rated across South Dakota

Refined Aesthetics
Sioux falls
Medical spa in Sioux Falls, SD · 5★ (721).

Serenity Spa & Facials Sioux Falls
Sioux falls
Facial spa in Sioux Falls, SD · 4.8★ (529).
JMISKO surgical design | md
Sioux falls
Medical spa in Sioux Falls, SD · 4.9★ (466).

Encompass Wellness & Aesthetics
Sioux falls
Wellness center in Sioux Falls, SD · 4.9★ (415).

Vital Flow Infusions
Sioux falls
Medical spa in Downtown, SD · 5★ (268).

Novo Aesthetics
Sioux falls
Medical spa in Sioux Falls, SD · 5★ (228).

Infinity Medical Aesthetics
Sioux falls
Medical spa in Sioux Falls, SD · 5★ (197).

Liv Med Spa | Sioux Falls, SD
Sioux falls
Medical spa in Sioux Falls, SD · 5★ (153).
Lazaderm
Sioux falls
Medical spa in Sioux Falls, SD · 4.9★ (140).
South Dakota med spa FAQ
How many med spas are in South Dakota?
MedSpa Compass lists 20 med spas and aesthetic clinics across South Dakota in Sioux Falls, ranked by Google review volume and rating.
How much does Botox cost in South Dakota?
Across South Dakota, med spas typically charge about $11–$15 per unit for Botox. A common treatment uses 20–40 units, so a session usually runs roughly $220–$600. Per-unit pricing varies by city, provider and brand (Botox vs Dysport) — open a city below for local ranges.
Where are the med spas in South Dakota?
Sioux Falls is the main med spa hub in South Dakota, with 20 clinics in our directory. Browse them ranked by rating and reviews above.
Are med spas in South Dakota regulated?
Yes — in South Dakota, med spa treatments such as injectables and lasers are performed or supervised by licensed medical professionals under a physician. Always confirm a clinic's medical director and injector credentials before booking.