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Weight Loss (GLP-1) · Sioux Falls, SD

Weight Loss (GLP-1) in Sioux Falls

6 clinics · ranked by rating & reviews · updated 2026

Medical weight-loss programs at med spas are provider-supervised programs that may combine prescription medication, nutrition guidance and regular monitoring. These are medical programs — eligibility, suitability and treatment are decided by a licensed provider after an assessment. The clinics below offer medical weight-loss services; a consultation is the starting point.

Below are 6 med spas offering weight loss (glp-1) in Sioux Falls, SD, ranked by Google review volume so you can start with the most established options and contact them directly.

Typical pricing in Sioux Falls

Typical Sioux Falls pricing: roughly $11–15 per unit for Botox, $575–1,000 per syringe for filler, and $160–340 per session for HydraFacial or microneedling. Packages and memberships are common — confirm the rate at consultation.

See our full guide to med spas in Sioux Falls for neighborhoods, local pricing and how to choose.

Top weight loss (glp-1) clinics in Sioux Falls

  1. 1
    Refined Aesthetics
    Med Spa

    Refined Aesthetics

    Sioux falls

    Medical spa in Sioux Falls, SD · 5★ (721).

    ★ 5 · 721View →
  2. 2
    Encompass Wellness & Aesthetics
    Med Spa

    Encompass Wellness & Aesthetics

    Sioux falls

    Wellness center in Sioux Falls, SD · 4.9★ (415).

    ★ 4.9 · 415View →
  3. 3
    Novo Aesthetics
    Med Spa

    Novo Aesthetics

    Sioux falls

    Medical spa in Sioux Falls, SD · 5★ (228).

    ★ 5 · 228View →
  4. 4
    Liv Med Spa | Sioux Falls, SD
    Med Spa

    Liv Med Spa | Sioux Falls, SD

    Sioux falls

    Medical spa in Sioux Falls, SD · 5★ (153).

    ★ 5 · 153View →
  5. 5
    The Confidence Collective
    Med Spa

    The Confidence Collective

    Sioux falls

    Medical spa in Sioux Falls, SD · 5★ (133).

    ★ 5 · 133View →
  6. 6
    Lisa's Lil Spa Room
    Med Spa

    Lisa's Lil Spa Room

    Sioux falls

    Facial spa in Sioux Falls, SD · 4.7★ (57).

    ★ 4.7 · 57View →

FAQ

Weight Loss (GLP-1) in Sioux Falls — common questions

How much does a medical weight-loss program cost? +
Pricing varies widely by clinic and program and is often monthly. Because these are medical programs, the cost and what is included are confirmed at a consultation with a licensed provider.
Is it medically supervised? +
Yes — reputable programs are supervised by a licensed medical provider who determines eligibility and the appropriate plan for you. This page lists clinics that offer such programs.
How do I get started? +
Book a consultation with a clinic offering medical weight loss. A licensed provider will assess whether a program is appropriate and explain the details.
How much does Botox cost in Sioux Falls? +
Most Sioux Falls med spas charge about $11–15 per unit, and a typical treatment uses 20–40 units. Confirm the per-unit rate and number of units quoted before booking.
Are med spas in South Dakota regulated? +
Medical spas in South Dakota operate under a licensed physician, and injectables and laser treatments should be performed or supervised by qualified medical professionals. Look for a named medical director and licensed injectors.
What should I look for when choosing a med spa in Sioux Falls? +
Prioritize a licensed medical team, transparent pricing, real before-and-after photos and a consultation before any treatment. High review counts help, but verify credentials first.
Which Sioux Falls areas have the most med spas? +
Downtown, western Sioux Falls and the Cathedral District have the highest concentration. Use the list below to compare clinics by rating, reviews and treatments.

Weight Loss (GLP-1) in other cities

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Other treatments in Sioux Falls

Laser Hair RemovalBotox & DysportLip & Dermal FillersCoolSculptingHydraFacialMicroneedlingIV Therapy